Native N-glycome profiling of single cells and ng-level blood isolates using label-free capillary electrophoresis-mass spectrometry
Abstract The development of reliable single-cell dispensers and substantial sensitivity improvement in mass spectrometry made proteomic profiling of individual cells achievable. Yet, there are no established methods for single-cell glycome analysis due to the inability to amplify glycans and sample...
Автори: | , , |
---|---|
Формат: | Стаття |
Мова: | English |
Опубліковано: |
Nature Portfolio
2024-05-01
|
Серія: | Nature Communications |
Онлайн доступ: | https://doi.org/10.1038/s41467-024-47772-w |