Kaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment, and breast cancer survival

Kaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment, and breast cancer survival

Through automated image analysis, Singhal et al quantify nuclear versus cytoplasmic distribution of the Kaiso transcription factor in breast cancer patient tissue. They find that Kaiso distribution correlates with breast cancer subtype and overall survival, and discover a link between cytoplasmic Ka...

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Bibliographic Details
Main Authors: Sandeep K. Singhal, Jung S. Byun, Samson Park, Tingfen Yan, Ryan Yancey, Ambar Caban, Sara Gil Hernandez, Stephen M. Hewitt, Heike Boisvert, Stephanie Hennek, Mark Bobrow, Md Shakir Uddin Ahmed, Jason White, Clayton Yates, Andrew Aukerman, Rami Vanguri, Rohan Bareja, Romina Lenci, Paula Lucia Farré, Adriana De Siervi, Anna María Nápoles, Nasreen Vohra, Kevin Gardner
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01651-y

Internet

https://doi.org/10.1038/s42003-021-01651-y

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