Metformin Triggers Apoptosis and Induction of the G0/G1 Switch 2 Gene in Macrophages

Metformin Triggers Apoptosis and Induction of the G0/G1 Switch 2 Gene in Macrophages

Metformin is a widely used antidiabetic drug for the treatment of type 2 diabetes and has been recently demonstrated to possess anti-inflammatory properties via AMPK-mediated modulation of M2 macrophage activation. However, the anti-inflammatory mechanisms of metformin on inflammatory macrophages ar...

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Bibliographic Details
Main Authors: Xuming Hu, Huan Luo, Chunfeng Dou, Xujing Chen, Yi Huang, Liping Wang, Songlei Xue, Zhen Sun, Shihao Chen, Qi Xu, Tuoyu Geng, Xin Zhao, Hengmi Cui
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Genes
Subjects:
macrophages
metformin
apoptosis
G0S2
Bcl-2
Online Access:https://www.mdpi.com/2073-4425/12/9/1437

Internet

https://www.mdpi.com/2073-4425/12/9/1437

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