Effect of Lipid Additives and Drug on the Rheological Properties of Molten Paraffin Wax, Degree of Surface Drug Coating, and Drug Release in Spray-Congealed Microparticles
Paraffin wax is potentially useful for producing spray-congealed drug-loaded microparticles with sustained-release and taste-masking properties. To date, there is little information about the effects of blending lipids with paraffin wax on the melt viscosity. In addition, drug particles may not be e...
Main Authors: | Hongyi Ouyang, Audrey Yi Zheng, Paul Wan Sia Heng, Lai Wah Chan |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-06-01
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Series: | Pharmaceutics |
Subjects: | |
Online Access: | http://www.mdpi.com/1999-4923/10/3/75 |
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