Assessing agreement between different polygenic risk scores in the UK Biobank

Abstract Polygenic risk scores (PRS) are proposed for use in clinical and research settings for risk stratification. However, there are limited investigations on how different PRS diverge from each other in risk prediction of individuals. We compared two recently published PRS for each of three cond...

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Bibliographic Details
Main Authors: Lei Clifton, Jennifer A. Collister, Xiaonan Liu, Thomas J. Littlejohns, David J. Hunter
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-17012-6