Contralateral Astrocyte Response to Acute Optic Nerve Damage Is Mitigated by PANX1 Channel Activity

Contralateral Astrocyte Response to Acute Optic Nerve Damage Is Mitigated by PANX1 Channel Activity

Glial reactivity is considered a hallmark of damage-induced innate immune responses in the central nervous system. In the visual system, unilateral optic nerve damage elicits dramatic glial reactivity in the retina directly affected by the lesion and a similar, albeit more modest, effect in the cont...

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Bibliographic Details
Main Authors: Jasmine A. Wurl, Caitlin E. Mac Nair, Joel A. Dietz, Valery I. Shestopalov, Robert W. Nickells
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
astrocyte
Müller cell
unilateral optic nerve damage
contralateral retina
PANX1 hemichannels
Online Access:https://www.mdpi.com/1422-0067/24/21/15641

Internet

https://www.mdpi.com/1422-0067/24/21/15641

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