The Genetic Dissection of Ace2 Expression Variation in the Heart of Murine Genetic Reference Population

The Genetic Dissection of Ace2 Expression Variation in the Heart of Murine Genetic Reference Population

Background: A high inflammatory and cytokine burden that induces vascular inflammation, myocarditis, cardiac arrhythmias, and myocardial injury is associated with a lethal outcome in COVID-19. The SARS-CoV-2 virus utilizes the ACE2 receptor for cell entry in a similar way to SARS-CoV. This study inv...

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Bibliographic Details
Main Authors: Fuyi Xu, Jun Gao, Undral Munkhsaikhan, Ning Li, Qingqing Gu, Joseph F. Pierre, Athena Starlard-Davenport, Jeffrey A. Towbin, Yan Cui, Enkhsaikhan Purevjav, Lu Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
BXD mice
cardiovascular
ACE2
gene regulaiton
COVID-19
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2020.582949/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2020.582949/full

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