Optimization of Goat Milk with ACE Inhibitory Peptides Fermented by Lactobacillus bulgaricus LB6 Using Response Surface Methodology

Optimization of Goat Milk with ACE Inhibitory Peptides Fermented by Lactobacillus bulgaricus LB6 Using Response Surface Methodology

In the present study, the incubation conditions of goat milk fermented by Lactobacillus bulgaricus LB6 were optimized to increase the angiotensin converting enzyme (ACE, EC 3.4.15.1) inhibitory activity by Box–Behnken design of response surface methodology. Incubation temperature, whey powder, and c...

Full description

Bibliographic Details
Main Authors:	Guowei Shu, Xiaoyu Shi, He Chen, Zhe Ji, Jiangpeng Meng
Format:	Article
Language:	English
Published:	MDPI AG 2017-11-01
Series:	Molecules
Subjects:	goat milk fermentation conditions ACE inhibitory activity Box–Behnken design
Online Access:	https://www.mdpi.com/1420-3049/22/11/2001

Similar Items

Effect of Enzymolysis and in Vitro Simulated Gastrointestinal Digestion on the ACE Inhibitory Activity of Defatted Goat Milk Powder
by: Weijie TIAN, et al.
Published: (2023-05-01)

Effect of Different Proteases on the Degree of Hydrolysis and Angiotensin I-Converting Enzyme-Inhibitory Activity in Goat and Cow Milk
by: Guowei Shu, et al.
Published: (2018-09-01)

Identification of potential ACE-inhibitory peptides from dromedary fermented camel milk
by: Omar Amin Alhaj
Published: (2017-04-01)

Collaborative optimization and molecular docking exploration of novel ACE-inhibitory peptides from bovine milk by complex proteases hydrolysis
by: Li Chen, et al.
Published: (2020-01-01)

Goat Milk Protein-Derived ACE Inhibitory Peptide SLPQ Exerts Hypertension Alleviation Effects Partially by Regulating the Inflammatory Stress of Endothelial Cells
by: Shenghao Xing, et al.
Published: (2024-10-01)

Study on the preparation of ACE inhibitory peptides by probiotic fermentation of quinoa
by: LI Shuai, et al.
Published: (2022-10-01)

Milk Fermentation by <i>Lacticaseibacillus rhamnosus</i> GG and <i>Streptococcus thermophilus</i> SY-102: Proteolytic Profile and ACE-Inhibitory Activity
by: Jessica Lizbeth Sebastián-Nicolas, et al.
Published: (2021-10-01)

Peptidomics approaches to the discovery and ACE inhibitory effect of casein peptides derived from fermented bovine milk by kefir grains
by: Bo Wang, et al.
Published: (2023-09-01)

Optimization of High-yield ACE Inhibitory Peptide Fermented Milk by Response Surface Methodology and Its Texture and Flavor Characteristics
by: Jiaxu WANG, et al.
Published: (2023-10-01)

Integrated Continuous Bioprocess Development for ACE-Inhibitory Peptide Production by Lactobacillus helveticus Strains in Membrane Bioreactor
by: Cyril Raveschot, et al.
Published: (2020-09-01)

Inhibitory effect of goat and cow milk fermented by Bifidobacterium longum on Serratia marcescens and Campylobacter jejuni
by: Hrvoje Pavlović, et al.
Published: (2006-08-01)

Biofunctional Attributes and Storage Study of Soy Milk Fermented by Lactobacillus rhamnosus and Lactobacillus helveticus
by: Birendra Kumar Mishra, et al.
Published: (2019-01-01)

Identification of a Novel ACE-inhibitory Peptide from Sheep Casein and Evaluation of the Molecular Binding Mechanism
by: Haixia TANG, et al.
Published: (2022-01-01)

Quantitative Structure–Activity Relationship Models for the Angiotensin-Converting Enzyme Inhibitory Activities of Short-Chain Peptides of Goat Milk Using Quasi-SMILES
by: Alla P. Toropova, et al.
Published: (2024-06-01)

In Vitro ACE Inhibitory Activity and Bioactive Compounds of Aqueous Extract of Citrus amblycarpa
by: I Gusti Ayu Wita Kusumawati, et al.
Published: (2021-08-01)

Inhibitory effect of goat and cow milk fermented with Bifidobacterium longum bb-46 on growth of uropathogenic Candida albicans
by: Vedran Slačanac, et al.
Published: (2004-10-01)

Identification of a Novel ACE Inhibitory Hexapeptide from Camellia Seed Cake and Evaluation of Its Stability
by: Qiaonan Zhu, et al.
Published: (2023-01-01)

ACE2-Inhibitory Effects of Bromelain and Ficin in Colon Cancer Cells
by: Babak Pakbin, et al.
Published: (2023-02-01)

Jack Bean (Canavalia ensiformis) Tempeh: ACE-Inhibitory Peptide Formation during Absorption in the Small Intestine
by: Endah Puspitojati, et al.
Published: (2023-01-01)

Separation and Purification of ACE Inhibitory Peptide from Jellyfish by Macroporous Resin
by: Tingting CUI, et al.
Published: (2022-05-01)

Revealing the Sequence Characteristics and Molecular Mechanisms of ACE Inhibitory Peptides by Comprehensive Characterization of 160,000 Tetrapeptides
by: Mingzhe Ma, et al.
Published: (2023-04-01)

Three Novel ACE Inhibitory Peptides Isolated From Ginkgo biloba Seeds: Purification, Inhibitory Kinetic and Mechanism
by: Fei-Fei Ma, et al.
Published: (2019-01-01)

Bio-functional, antibacterial, ACE and DPP-IV inhibitory activities of thyme, flax and apple pollen-peptides by controlled enzymolysis
by: Zahra Akbarbaglu, et al.
Published: (2025-03-01)

Preparation of corn ACE inhibitory peptide-ferrous chelate by dual-frequency ultrasound and its structure and stability analyses
by: Wenjuan Qu, et al.
Published: (2022-02-01)

Isolation, purification and identification of ACE inhibitory peptide from Paramisgurnus dabryanus protein
by: DONG Jing-qi, et al.
Published: (2023-02-01)

Physicochemical Properties of ACE Inhibitory Peptides from Jujube Kernel by Enzymatic Method
by: Liming TAN, et al.
Published: (2022-01-01)

Optimization of the extraction process of ACE inhibitory peptides from distillery waste and their antioxidant activity
by: YAO Mingcai, et al.
Published: (2024-10-01)

Research progress on ACE immobilization and immobilized ACE used for affinity separation and enrichment of food-derived antihypertensive peptides
by: ZHANG Jingjing, et al.
Published: (2024-10-01)

Optimization of Enzymatic Hydrolysis Process and Activity of ACE Inhibitory Peptides from Selenium-rich Moringa oleifera Leaves Protein
by: Bingbing CHEN, et al.
Published: (2022-02-01)

Separation and Characterization of Angiotensin I Converting Enzyme (ACE) Inhibitory Peptides from Saurida elongata Proteins Hydrolysate by IMAC-Ni2+
by: Lixia Sun, et al.
Published: (2017-02-01)

A novel ACE inhibitory peptide from Pelodiscus sinensis Wiegmann meat water-soluble protein hydrolysate
by: Pengying Liao, et al.
Published: (2024-06-01)

Biological properties of LMW-peptide fractions from apricot kernel protein: Nutritional, antibacterial and ACE-inhibitory activities
by: Zahra Akbarbaglu, et al.
Published: (2024-06-01)

Preparation and Identification of ACE Inhibitory Peptides from the Marine Macroalga Ulva intestinalis
by: Siqi Sun, et al.
Published: (2019-03-01)

Volatile compounds, antioxidant activity, ACE inhibitory activity, HMF content and microstructure of fruit yoghurts
by: İhsan Bakirci, et al.
Published: (2023-01-01)

ACE Inhibitory Peptides Derived from Muscovy Duck (<i>Cairina moschata</i>) Plasma
by: Zongshuai Zhu, et al.
Published: (2022-12-01)

A New Probiotic Cheddar Cheese with High ACE-Inhibitory Activity and γ-Aminobutyric Acid Content Produced with Koumiss-Derived Lactobacillus casei Zhang
by: Hai Kuan Wang, et al.
Published: (2010-01-01)

Oral Administration of Fermented Milk from Co-Starter Containing <i>Lactobacillus plantarum</i> Y44 Shows an Ameliorating Effect on Hypertension in Spontaneously Hypertensive Rats
by: Jiang Yu, et al.
Published: (2024-02-01)

Novel angiotensin-converting enzyme inhibitory peptides from caseins and whey proteins of goat milk
by: Hisham R. Ibrahim, et al.
Published: (2017-01-01)

Preparation, Structure Identification of ACE Inhibitory Glycopeptide from Quinoa and Its Stability in Vitro
by: Yuyuan YU, et al.
Published: (2023-06-01)

Study on in Vitro Stability and Antioxidant Activity of ACE Inhibitory Peptide from Gracilaria lemaneiformis
by: Jiasen SHEN, et al.
Published: (2022-04-01)