Early Detection of Hypothermic Neuroprotection Using T2-Weighted Magnetic Resonance Imaging in a Mouse Model of Hypoxic Ischemic Encephalopathy

Early Detection of Hypothermic Neuroprotection Using T2-Weighted Magnetic Resonance Imaging in a Mouse Model of Hypoxic Ischemic Encephalopathy

Perinatal hypoxic-ischemic encephalopathy (HIE) can lead to neurodevelopmental disorders, including cerebral palsy. Standard care for neonatal HIE includes therapeutic hypothermia, which provides partial neuroprotection; magnetic resonance imaging (MRI) is often used to assess injury and predict out...

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Bibliographic Details
Main Authors: Sydney E. Doman, Akanksha Girish, Christina L. Nemeth, Gabrielle T. Drummond, Patrice Carr, Maxine S. Garcia, Michael V. Johnston, Sujatha Kannan, Ali Fatemi, Jiangyang Zhang, Mary Ann Wilson
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Neurology
Subjects:
hypothermia
neuroprotection
hypoxic-ischemic
neonatal encephalopathy
magnetic resonance imaging
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2018.00304/full

Internet

http://journal.frontiersin.org/article/10.3389/fneur.2018.00304/full

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