Adropin inhibits the progression of atherosclerosis in ApoE-/-/Enho-/- mice by regulating endothelial-to-mesenchymal transition

Abstract Adropin, a secreted protein, coded by energy homeostasis-associated gene (Enho), is recently reported to modulate atherogenesis, with endothelial-to-mesenchymal transition (EndMT) involved in the early process. We explored whether adropin may alleviate atherosclerosis by regulating EndMT. W...

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Bibliographic Details
Main Authors: Teng Ying, LingZhen Wu, TingXiang Lan, ZhiXiong Wei, DanQing Hu, YiLang Ke, Qiong Jiang, Jun Fang
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01697-3