Cryptic glucocorticoid receptor-binding sites pervade genomic NF-κB response elements
Glucocorticoid receptor (GR) regulates immunity and inflammation but the mechanisms by which GR represses proinflammatory genes are still being debated. Here the authors use a multidisciplinary approach and show that GR binds to a cryptic site within genome-wide NFκB DNA response elements to repress...
Príomhchruthaitheoirí: | , , , , , , , , , |
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Formáid: | Alt |
Teanga: | English |
Foilsithe / Cruthaithe: |
Nature Portfolio
2018-04-01
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Sraith: | Nature Communications |
Rochtain ar líne: | https://doi.org/10.1038/s41467-018-03780-1 |