Mapping the Transcriptional and Fitness Landscapes of a Pathogenic <i>E. coli</i> Strain: The Effects of Organic Acid Stress under Aerobic and Anaerobic Conditions

Mapping the Transcriptional and Fitness Landscapes of a Pathogenic <i>E. coli</i> Strain: The Effects of Organic Acid Stress under Aerobic and Anaerobic Conditions

Several methods are available to probe cellular responses to external stresses at the whole genome level. RNAseq can be used to measure changes in expression of all genes following exposure to stress, but gives no information about the contribution of these genes to an organism’s ability to survive...

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Bibliographic Details
Main Authors: Francesca Bushell, John M. J. Herbert, Thippeswamy H. Sannasiddappa, Daniel Warren, A. Keith Turner, Francesco Falciani, Peter A. Lund
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Genes
Subjects:
acid stress
organic acid
SCFA
short-chain fatty acid
gastrointestinal tract
uropathogenic <i>E. coli</i>
Online Access:https://www.mdpi.com/2073-4425/12/1/53

Internet

https://www.mdpi.com/2073-4425/12/1/53

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