A versatile method for the identification of senolytic compounds

A versatile method for the identification of senolytic compounds

The increased burden of senescent cells is as a well-established hallmark of aging and age-related diseases. This finding sparked significant interest in the identification of molecules capable of selectively eliminating senescent cells, so-called senolytics. Here, we fine-tuned a method for the ide...

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Bibliographic Details
Main Authors: Chiara Annunziata, Francesca Castoldi, Jan Schlegel, Hazel X. Ang, Mina Ristovska, Stefania Melini, Robert Welch, Christian G. Riedel, Federico Pietrocola
Format: Article
Language:English
Published: Shared Science Publishers OG 2023-12-01
Series:Cell Stress
Subjects:
cell death
senescence
nucleus
fluorescence microscopy
navitoclax
Online Access:http://www.cell-stress.com/researcharticles/2023a-annunziata-cell-stress/

Internet

http://www.cell-stress.com/researcharticles/2023a-annunziata-cell-stress/

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