Specialized active leprosy search strategies in an endemic area of the Brazilian Amazon identifies a hypermutated Mycobacterium leprae strain causing primary drug resistance

Specialized active leprosy search strategies in an endemic area of the Brazilian Amazon identifies a hypermutated Mycobacterium leprae strain causing primary drug resistance

IntroductionLeprosy, an infectious disease caused by Mycobacterium leprae, remains a public health concern in endemic countries, particularly in Brazil. In this study, we conducted an active surveillance campaign in the hyperendemic city of Castanhal in the northeastern part of the state of Pará usi...

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Main Authors: Raquel Carvalho Bouth, Angélica Rita Gobbo, Josafá Gonçalves Barreto, Pablo Diego do Carmo Pinto, Maraya Semblano Bittencourt, Marco Andrey Cipriani Frade, Apolônio Carvalho Nascimento, Sabrina Sampaio Bandeira, Patricia Fagundes da Costa, Guilherme Augusto Barros Conde, Charlotte Avanzi, Ândrea Ribeiro-dos-Santos, John Stewart Spencer, Moises Batista da Silva, Claudio Guedes Salgado
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Medicine
Subjects:
leprosy
Mycobacterium leprae
household contacts
school children
drug resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1243571/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2023.1243571/full

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