Therapeutic equine hyperimmune antibodies with high and broad-spectrum neutralizing activity protect rodents against SARS-CoV-2 infection

Therapeutic equine hyperimmune antibodies with high and broad-spectrum neutralizing activity protect rodents against SARS-CoV-2 infection

The emergence of SARS-CoV-2 variants stresses the continued need for broad-spectrum therapeutic antibodies. Several therapeutic monoclonal antibodies or cocktails have been introduced for clinical use. However, unremitting emerging SARS-CoV-2 variants showed reduced neutralizing efficacy by vaccine...

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Bibliographic Details
Main Authors: Entao Li, Qiuxue Han, Jinhao Bi, Shimeng Wei, Shen Wang, Ying Zhang, Jun Liu, Na Feng, Tiecheng Wang, Jun Wu, Songtao Yang, Yongkun Zhao, Bo Liu, Feihu Yan, Xianzhu Xia
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
equine antibody
variants of concern
variants of interest
broad-spectrum neutralizing activity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1066730/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1066730/full

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