Barriers in the Brain: Resolving Dendritic Spine Morphology and Compartmentalization

Barriers in the Brain: Resolving Dendritic Spine Morphology and Compartmentalization

Dendritic spines are micron-sized protrusions that harbor the majority of excitatory synapses in the central nervous system. The head of the spine is connected to the dendritic shaft by a 50-400 nm thin membrane tube, called the spine neck, which has been hypothesized to confine biochemical and elec...

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Bibliographic Details
Main Authors: Max eAdrian, Remy eKusters, Corette J Wierenga, Cornelis eStorm, Casper C Hoogenraad, Lukas C Kapitein
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Neuroanatomy
Subjects:
Dendritic Spines
Diffusion
compartmentalization
mathematical modelling
super-resolution microscopy
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnana.2014.00142/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnana.2014.00142/full

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