Potentiation of combined p19Arf and interferon-beta cancer gene therapy through its association with doxorubicin chemotherapy

Abstract Balancing safety and efficacy is a major consideration for cancer treatments, especially when combining cancer immunotherapy with other treatment modalities such as chemotherapy. Approaches that induce immunogenic cell death (ICD) are expected to eliminate cancer cells by direct cell killin...

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Bibliographic Details
Main Authors: Ruan F. V. Medrano, Thiago A. Salles, Rafael Dariolli, Fernanda Antunes, Valker A. Feitosa, Aline Hunger, João P. P. Catani, Samir A. Mendonça, Rodrigo E. Tamura, Marlous G. Lana, Elaine G. Rodrigues, Bryan E. Strauss
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-17775-y