High molecular weight sodium hyaluronate improves survival of syndecan-1-deficient septic mice by inhibiting neutrophil migration.

High molecular weight sodium hyaluronate improves survival of syndecan-1-deficient septic mice by inhibiting neutrophil migration.

<h4>Methods</h4>Sepsis was induced by cotton smoke inhalation followed by intranasal administration of Pseudomonas aeruginosa in female (> 6 months) Balb/c and syndecan-1 knockout mice. Survival of mice, lung capillary endothelial glycocalyx integrity, lung water content, and vascular...

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Main Authors: Tuvshintugs Baljinnyam, Enkhtuya Radnaa, Casey M Ouellette, Christina Nelson, Yosuke Niimi, Clark R Andersen, Vsevolod Popov, Jae-Woo Lee, Donald S Prough, Perenlei Enkhbaatar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0250327&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0250327&type=printable

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