Novel mutations in PLCZ1 lead to early embryonic arrest as a male factor

Novel mutations in PLCZ1 lead to early embryonic arrest as a male factor

Early embryonic arrest is one of the causes of assist reproduction technology (ART) failure. We have previously reported that the first sperm-derived genetic factor, ACTL7a mutations, could lead to early embryonic arrest. However, whether there are other male genetic factors associated with early em...

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Bibliographic Details
Main Authors: Yunying Lin, Yi Huang, Boyu Li, Ting Zhang, Yichao Niu, Shuanggang Hu, Ying Ding, Guangxin Yao, Zhe Wei, Ning Yao, Yejie Yao, Yao Lu, Yaqiong He, Qinling Zhu, Ling Zhang, Yun Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
male infertility
PLCZ1 bi-allelic mutation
early embryonic developmental arrest
polyspermy
ICSI with AOA
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1193248/full

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https://www.frontiersin.org/articles/10.3389/fcell.2023.1193248/full

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