The ITIM-Containing Receptor: Leukocyte-Associated Immunoglobulin-Like Receptor-1 (LAIR-1) Modulates Immune Response and Confers Poor Prognosis in Invasive Breast Carcinoma

Background: The leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) plays a role in immune response homeostasis, extracellular matrix remodelling and it is overexpressed in many high-grade cancers. This study aimed to elucidate the biological and prognostic role of LAIR-1 in invasive breast...

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Main Authors: Chitra Joseph, Mansour A. Alsaleem, Michael S. Toss, Yousif A. Kariri, Maryam Althobiti, Sami Alsaeed, Abrar I. Aljohani, Pavan L. Narasimha, Nigel P. Mongan, Andrew R. Green, Emad A. Rakha
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/1/80