A framework of computer vision-enhanced microfluidic approach for automated assessment of the transient sickling kinetics in sickle red blood cells

A framework of computer vision-enhanced microfluidic approach for automated assessment of the transient sickling kinetics in sickle red blood cells

The occurrence of vaso-occlusive crisis greatly depends on the competition between the sickling delay time and the transit time of individual sickle cells, i.e., red blood cells from sickle cell disease (SCD) patients, while they are traversing the circulatory system. Many drugs for treating SCD wor...

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Bibliographic Details
Main Authors: Yuhao Qiang, Mengjia Xu, Mira Patel Pochron, Madhulika Jupelli, Ming Dao
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Physics
Subjects:
deep learning
microfluidics
image segmentation and classification
drug testing
sickle cell disease
automated sickling kinetics assay
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2024.1331047/full

Internet

https://www.frontiersin.org/articles/10.3389/fphy.2024.1331047/full

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