Toxicological evaluation of PLA/PVA-naringenin nanoparticles: In vitro and in vivo studies

Toxicological evaluation of PLA/PVA-naringenin nanoparticles: In vitro and in vivo studies

In the present study, the safety profile of the polylactic acid/ polyvinyl alcohol-naringenin (PLA/PVA-Nar) nanoparticles was evaluated. The analysis of cell viability, lactate dehydrogenase (LDH) leakage, and generation of reactive oxygen species (ROS) in the Caco-2 cell line showed no significant...

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Bibliographic Details
Main Authors: Smruthi MR, Ilaiyaraja Nallamuthu, Dongzagin Singsit, T. Anand
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:OpenNano
Subjects:
Cytotoxicity
Serum parameters
Histopathology
Hematology
Antioxidant enzymes
Online Access:http://www.sciencedirect.com/science/article/pii/S2352952022000196

Internet

http://www.sciencedirect.com/science/article/pii/S2352952022000196

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