Calpain inhibitors inhibit mitochondrial calpain activity to ameliorate apoptosis of cocultured myoblast

Calpain inhibitors inhibit mitochondrial calpain activity to ameliorate apoptosis of cocultured myoblast

Cancer cachexia is a fatal syndrome associated with muscle regeneration disability. Tumor factors induce the apoptosis of myoblasts to impair the regeneration of skeletal muscle. Cancer cachectic myoblast apoptosis is associated with mitochondria injury. It has been reported that activated mitochond...

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Bibliographic Details
Main Authors: Xianliang Zeng, Li Zhao, Zhengliang Chen, Lingjun Kong, Sizeng Chen
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Chinese Journal of Physiology
Subjects:
apoptosis
calpain
cancer cachexia
mitochondria
myoblast
Online Access:http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2022;volume=65;issue=5;spage=226;epage=232;aulast=Zeng

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http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2022;volume=65;issue=5;spage=226;epage=232;aulast=Zeng

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