Potential application of proteolysis targeting chimera (PROTAC) modification technology in natural products for their targeted protein degradation

There are numerous evaluations of natural products, of which majority are food bioactives, performed up to date for their various health beneficial activities via targeting specific proteins. However, the direct identification of a targeted protein remains unexplored for natural occurring compounds....

Full description

Bibliographic Details
Main Authors: Guliang Yang, Haiyan Zhong, Xinxin Xia, Zhiwen Qi, Chengzhang Wang, Shiming Li
Format: Article
Language:English
Published: Tsinghua University Press 2022-03-01
Series:Food Science and Human Wellness
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213453021000951