PEG-IFN alpha but not ribavirin alters NK cell phenotype and function in patients with chronic hepatitis C.

PEG-IFN alpha but not ribavirin alters NK cell phenotype and function in patients with chronic hepatitis C.

Ribavirin (RBV) remains part of several interferon-free treatment strategies even though its mechanisms of action are still not fully understood. One hypothesis is that RBV increases responsiveness to type I interferons. Pegylated Interferon alpha (PEG-IFNa) has recently been shown to alter natural...

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Bibliographic Details
Main Authors: Antoaneta A Markova, Ulrike Mihm, Verena Schlaphoff, Sebastian Lunemann, Natalie Filmann, Birgit Bremer, Thomas Berg, Christoph Sarrazin, Stefan Zeuzem, Michael P Manns, Markus Cornberg, Eva Herrmann, Heiner Wedemeyer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3994015?pdf=render

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http://europepmc.org/articles/PMC3994015?pdf=render

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