Integration of transcriptomics and metabolomics reveals the responses of the maternal circulation and maternal-fetal interface to LPS-induced preterm birth in mice

Integration of transcriptomics and metabolomics reveals the responses of the maternal circulation and maternal-fetal interface to LPS-induced preterm birth in mice

BackgroundTerm birth (TB) and preterm birth (PTB) are characterized by uterine contractions, rupture of the chorioamniotic membrane, decidual activation, and other physiological and pathological changes. In this study, we hypothesize that inflammation can cause changes in mRNA expression and metabol...

Full description

Bibliographic Details
Main Authors: Xianling Cao, Xuanyou Zhou, Songchang Chen, Chenming Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Immunology
Subjects:
maternal-fetal interface
transcriptomics
metabolomics
preterm birth
mice
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1213902/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1213902/full

Similar Items