The effect of aquaporin-4 mis-localization on Aβ deposition in mice

The reduced clearance of amyloid-β (Aβ) is thought to contribute to the development of the pathology associated with Alzheimer's disease (AD), which is characterized by the deposition of Aβ plaques. Previous studies have shown that Aβ is cleared via the glymphatic system, a brain-wide network o...

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Bibliographic Details
Main Authors: Taylor J. Pedersen, Samantha A. Keil, Warren Han, Marie X. Wang, Jeffrey J. Iliff
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996123001146