What can go wrong when observations are not independently and identically distributed: A cautionary note on calculating correlations on combined data sets from different experiments or conditions

In the scientific literature data analysis results are often presented when samples from different experiments or different conditions, technical replicates or times series are merged to increase the sample size before calculating the correlation coefficient. This way of proceeding violates two basi...

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Bibliographic Details
Main Author: Edoardo Saccenti
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Systems Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fsysb.2023.1042156/full