Exosomes Derived From Mesenchymal Stromal Cells Pretreated With Advanced Glycation End Product-Bovine Serum Albumin Inhibit Calcification of Vascular Smooth Muscle Cells

Exosomes Derived From Mesenchymal Stromal Cells Pretreated With Advanced Glycation End Product-Bovine Serum Albumin Inhibit Calcification of Vascular Smooth Muscle Cells

Background: The osteogenic differentiation of vascular smooth muscle cell (VSMCs) is important for the development of vascular calcification (VC), particularly in diabetes. Exosomes derived from Mesenchymal Stromal Cells (MSCs) are effective against cardiovascular diseases, yet their role in VC rema...

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Bibliographic Details
Main Authors: Ying Wang, Wen-Qi Ma, Yi Zhu, Xi-Qiong Han, Naifeng Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Endocrinology
Subjects:
advanced glycation end products
vascular calcification
BMSC
exosome
miR-146a
TXNIP
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00524/full

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https://www.frontiersin.org/article/10.3389/fendo.2018.00524/full

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