Sexual dimorphic impacts of systemic vincristine on lower urinary tract function

Abstract Vincristine (VCR) is one of the most common chemotherapy agents used in pediatric oncology. Despite the well-known VCR-induced peripheral neuropathy, potential impacts of VCR on lower urinary tract (LUT) function remain poorly defined. We investigated the effects of systemic VCR exposure in...

Full description

Bibliographic Details
Main Authors: Nao Iguchi, Sarah L. Hecht, Dexiang Gao, Duncan T. Wilcox, Anna P. Malykhina, Nicholas G. Cost
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-08585-3