Variance in brain volume with advancing age: implications for defining the limits of normality.

Statistical models of normal ageing brain tissue volumes may support earlier diagnosis of increasingly common, yet still fatal, neurodegenerative diseases. For example, the statistically defined distribution of normal ageing brain tissue volumes may be used as a reference to assess patient volumes....

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Bibliographic Details
Main Authors: David Alexander Dickie, Dominic E Job, David Rodriguez Gonzalez, Susan D Shenkin, Trevor S Ahearn, Alison D Murray, Joanna M Wardlaw
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3868601?pdf=render