A MetAP2 inhibitor blocks adipogenesis, yet improves glucose uptake in cells

Adipose tissue expansion involves angiogenesis to remodel its capillary network. The enzymemethionine aminopeptidase 2(MetAP2) promotes angiogenesis.MetAP2 inhibitors suppress angiogenesis and have potential anti-obesity effect. However, impairment in adipose tissue expansion is also linked with imp...

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Bibliographic Details
Main Authors: Md Abu Bakkar Siddik, Bhaskar C. Das, Louis Weiss, Nikhil V. Dhurandhar, Vijay Hegde
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Adipocyte
Subjects:
Online Access:http://dx.doi.org/10.1080/21623945.2019.1636627