Large numbers of patients are needed to obtain additional approvals for new cancer drugs: A retrospective cohort study

Abstract Patients endure risk and uncertainty when they participate in clinical trials. We previously estimated that 12,217 patient-participants are required to bring a new cancer drug to market. However, many development efforts are aimed at extending the label of already approved drugs. Herein, we...

Full description

Bibliographic Details
Main Authors: Charlotte Ouimet, Nora Hutchinson, Catherine Wang, Carol Matyka, Joseph C. Del Paggio, Jonathan Kimmelman
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-42213-y