DNA methylation in cocaine use disorder–An epigenome-wide approach in the human prefrontal cortex

DNA methylation in cocaine use disorder–An epigenome-wide approach in the human prefrontal cortex

BackgroundCocaine use disorder (CUD) is characterized by a loss of control over cocaine intake and is associated with structural, functional, and molecular alterations in the human brain. At the molecular level, epigenetic alterations are hypothesized to contribute to the higher-level functional and...

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Bibliographic Details
Main Authors: Eric Poisel, Lea Zillich, Fabian Streit, Josef Frank, Marion M. Friske, Jerome C. Foo, Naguib Mechawar, Gustavo Turecki, Anita C. Hansson, Markus M. Nöthen, Marcella Rietschel, Rainer Spanagel, Stephanie H. Witt
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Psychiatry
Subjects:
cocaine
DNA methylation
addiction
epigenetics
EWAS
prefrontal cortex
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1075250/full

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https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1075250/full

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