Liver-specific microRNA-185 knockout promotes cholesterol dysregulation in mice
Background: The liver plays a key role in regulating whole body cholesterol homeostasis. Hepatic cholesterol accumulation causes liver injury in fatty liver disease and hypercholesterolemia increases the risk of cardiovascular disease. MicroRNAs (miRNAs, miRs) have been shown to regulate various pat...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
KeAi Communications Co., Ltd.
2021-12-01
|
Series: | Liver Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2542568420300416 |