Stimulus-activated ribonuclease targeting chimeras for tumor microenvironment activated cancer therapy
Abstract RNA degradation using ribonuclease targeting chimeras (RiboTACs) is a promising approach for cancer therapy. However, potential off-target degradation is a serious issue. Here, a RiboTAC is designed for tumor microenvironment triggered activation. The tumor microenvironment activated RiboTA...
| Հիմնական հեղինակներ: | , , , , , , , , , , , , |
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| Ձևաչափ: | Հոդված |
| Լեզու: | English |
| Հրապարակվել է: |
Nature Portfolio
2025-02-01
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| Շարք: | Nature Communications |
| Առցանց հասանելիություն: | https://doi.org/10.1038/s41467-025-56691-3 |