Dopamine neuron glutamate cotransmission evokes a delayed excitation in lateral dorsal striatal cholinergic interneurons

Dopamine neuron glutamate cotransmission evokes a delayed excitation in lateral dorsal striatal cholinergic interneurons

Dopamine neurons have different synaptic actions in the ventral and dorsal striatum (dStr), but whether this heterogeneity extends to dStr subregions has not been addressed. We have found that optogenetic activation of dStr dopamine neuron terminals in mouse brain slices pauses the firing of choline...

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Bibliographic Details
Main Authors: Nao Chuhma, Susana Mingote, Leora Yetnikoff, Abigail Kalmbach, Thong Ma, Samira Ztaou, Anna-Claire Sienna, Sophia Tepler, Jean-Francois Poulin, Mark Ansorge, Rajeshwar Awatramani, Un Jung Kang, Stephen Rayport
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-10-01
Series:eLife
Subjects:
striatum
ventral midbrain
regional heterogeneity
glutamate cotransmission
metabotropic glutamate receptor 1
transient receptor potential channel
Online Access:https://elifesciences.org/articles/39786

Internet

https://elifesciences.org/articles/39786

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