STIP1/HOP Regulates the Actin Cytoskeleton through Interactions with Actin and Changes in Actin-Binding Proteins Cofilin and Profilin

STIP1/HOP Regulates the Actin Cytoskeleton through Interactions with Actin and Changes in Actin-Binding Proteins Cofilin and Profilin

Cell migration plays a vital role in both health and disease. It is driven by reorganization of the actin cytoskeleton, which is regulated by actin-binding proteins cofilin and profilin. Stress-inducible phosphoprotein 1 (STIP1) is a well-described co-chaperone of the Hsp90 chaperone system, and our...

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Bibliographic Details
Main Authors: Samantha Joy Beckley, Morgan Campbell Hunter, Sarah Naulikha Kituyi, Ianthe Wingate, Abantika Chakraborty, Kelly Schwarz, Matodzi Portia Makhubu, Robert Pierre Rousseau, Duncan Kyle Ruck, Jo-Anne de la Mare, Gregory Lloyd Blatch, Adrienne Lesley Edkins
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
<i>STIP1</i>
<i>STI1</i>
HOP
actin
ATPase activity
profilin
Online Access:https://www.mdpi.com/1422-0067/21/9/3152

Internet

https://www.mdpi.com/1422-0067/21/9/3152

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