Intestinal Drug Absorption Enhancement by Aloe vera Gel and Whole Leaf Extract: In Vitro Investigations into the Mechanisms of Action

Intestinal Drug Absorption Enhancement by Aloe vera Gel and Whole Leaf Extract: In Vitro Investigations into the Mechanisms of Action

The co-administration of absorption enhancing agents with macromolecular drugs (e.g., protein and peptide drugs) has been identified as a means to improve the oral bioavailability of these drugs. Absorption-enhancing agents of natural origins have received a great deal of attention due to their sust...

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Bibliographic Details
Main Authors: Anja Haasbroek, Clarissa Willers, Matthew Glyn, Lissinda du Plessis, Josias Hamman
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Pharmaceutics
Subjects:
Aloe vera
gel
whole leaf
absorption enhancement
Caco-2
confocal laser scanning microscopy
F-actin
FITC-dextran
tight junctions
transepithelial electrical resistance
Online Access:http://www.mdpi.com/1999-4923/11/1/36

Internet

http://www.mdpi.com/1999-4923/11/1/36

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