Cell Cycle Arrest and Cytotoxic Effects of SAHA and RG7388 Mediated through p21<sup>WAF1/CIP1</sup> and p27<sup>KIP1</sup> in Cancer Cells
<i>Background and Objective</i>: Alterations in gene expressions are often due to epigenetic modifications that can have a significant influence on cancer development, growth, and progression. Lately, histone deacetylase inhibitors (HDACi) such as suberoylanilide hydroxamic acid (SAHA, o...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-01-01
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| Series: | Medicina |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1010-660X/55/2/30 |