Enhanced inflammation and suppressed adaptive immunity in COVID-19 with prolonged RNA shedding

Enhanced inflammation and suppressed adaptive immunity in COVID-19 with prolonged RNA shedding

Abstract Little is known regarding why a subset of COVID-19 patients exhibited prolonged positivity of SARS-CoV-2 infection. Here, we found that patients with long viral RNA course (LC) exhibited prolonged high-level IgG antibodies and higher regulatory T (Treg) cell counts compared to those with sh...

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Bibliographic Details
Main Authors: Xiaohua Tang, Rui Sun, Weigang Ge, Tingting Mao, Liujia Qian, Chongquan Huang, Zhouyang Kang, Qi Xiao, Meng Luo, Qiushi Zhang, Sainan Li, Hao Chen, Wei Liu, Bingjie Wang, Shufei Li, Xiaoling Lin, Xueqin Xu, Huanzheng Li, Lianpeng Wu, Jianyi Dai, Huanhuan Gao, Lu Li, Tian Lu, Xiao Liang, Xue Cai, Guan Ruan, Fei Xu, Yan Li, Yi Zhu, Ziqing Kong, Jianping Huang, Tiannan Guo
Format: Article
Language:English
Published: Nature Publishing Group 2022-07-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-022-00441-y

Internet

https://doi.org/10.1038/s41421-022-00441-y

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