Assessment of plasma Catestatin in COVID-19 reveals a hitherto unknown inflammatory activity with impact on morbidity-mortality

Assessment of plasma Catestatin in COVID-19 reveals a hitherto unknown inflammatory activity with impact on morbidity-mortality

IntroductionNeuroendocrine cells release Catestatin (CST) from Chromogranin A (CgA) to regulate stress responses. As regards COVID-19 patients (COVID+) requiring oxygen supply, to date nobody has studied CST as a potential mediator in the regulation of immunity.Patients & MethodsAdmission pl...

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Bibliographic Details
Main Authors: Francis Schneider, Pierrick Le Borgne, Jean-Etienne Herbrecht, François Danion, Morgane Solis, Sophie Hellé, Cosette Betscha, Raphaël Clere-Jehl, François Lefebvre, Vincent Castelain, Yannick Goumon, Marie-Hélène Metz-Boutigue
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
Innate immunity
COVID
Catestatin
Chromogranin A
hypoxia
critically ill
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.985472/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.985472/full

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