Meta-analysis of integrated ChIP-seq and transcriptome data revealed genomic regions affected by estrogen receptor alpha in breast cancer

Meta-analysis of integrated ChIP-seq and transcriptome data revealed genomic regions affected by estrogen receptor alpha in breast cancer

Abstract Background The largest group of patients with breast cancer are estrogen receptor-positive (ER+) type. The estrogen receptor acts as a transcription factor and triggers cell proliferation and differentiation. Hence, investigating ER-DNA interaction genomic regions can help identify genes di...

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Bibliographic Details
Main Authors: Zeynab Piryaei, Zahra Salehi, Esmaeil Ebrahimie, Mansour Ebrahimi, Kaveh Kavousi
Format: Article
Language:English
Published: BMC 2023-09-01
Series:BMC Medical Genomics
Subjects:
Meta-analysis
ChIP-seq
RNA-seq
Breast cancer
Estrogen receptor-positive
MCF7/T47D cell lines
Online Access:https://doi.org/10.1186/s12920-023-01655-z

Internet

https://doi.org/10.1186/s12920-023-01655-z

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