A conserved Neurite Outgrowth and Guidance motif with biomimetic potential in neuronal Cell Adhesion Molecules

A conserved Neurite Outgrowth and Guidance motif with biomimetic potential in neuronal Cell Adhesion Molecules

The discovery of conserved protein motifs can, in turn, unveil important regulatory signals, and when properly designed, synthetic peptides derived from such motifs can be used as biomimetics for biotechnological and therapeutic purposes. We report here that specific Ig-like repeats from the extrace...

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Bibliographic Details
Main Authors: Giorgia Scapin, Matteo Gasparotto, Daniele Peterle, Simone Tescari, Elena Porcellato, Alberto Piovesan, Irene Righetto, Laura Acquasaliente, Vincenzo De Filippis, Francesco Filippini
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Neurite outgrowth
Axon guidance
Protein-protein interaction
NOG motif
Homophilic binding
Ig-like fold
Online Access:http://www.sciencedirect.com/science/article/pii/S200103702100427X

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http://www.sciencedirect.com/science/article/pii/S200103702100427X

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