Systemic effects of BMP2 treatment of fractures on non-injured skeletal sites during spaceflight

Systemic effects of BMP2 treatment of fractures on non-injured skeletal sites during spaceflight

Unloading associated with spaceflight results in bone loss and increased fracture risk. Bone morphogenetic protein 2 (BMP2) is known to enhance bone formation, in part, through molecular pathways associated with mechanical loading; however, the effects of BMP2 during spaceflight remain unclear. Here...

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Bibliographic Details
Main Authors: Ariane Zamarioli, Gremah Adam, Kevin A. Maupin, Paul J. Childress, Alexander Brinker, Joao P. B. Ximenez, Nabarun Chakraborty, Aarti Gautam, Rasha Hammamieh, Melissa A. Kacena
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Endocrinology
Subjects:
fracture repair
spaceflight
microgravity
bone mass
skeleton
bone morphogenetic protein
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.910901/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.910901/full

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