A primary cell-based in vitro model of the human small intestine reveals host olfactomedin 4 induction in response to Salmonella Typhimurium infection

A primary cell-based in vitro model of the human small intestine reveals host olfactomedin 4 induction in response to Salmonella Typhimurium infection

ABSTRACTInfection research largely relies on classical cell culture or mouse models. Despite having delivered invaluable insights into host-pathogen interactions, both have limitations in translating mechanistic principles to human pathologies. Alternatives can be derived from modern Tissue Engineer...

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Bibliographic Details
Main Authors: Thomas Däullary, Fabian Imdahl, Oliver Dietrich, Laura Hepp, Tobias Krammer, Christina Fey, Winfried Neuhaus, Marco Metzger, Jörg Vogel, Alexander J. Westermann, Antoine-Emmanuel Saliba, Daniela Zdzieblo
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Gut Microbes
Subjects:
Intestinal enteroids
biological scaffold
Salmonella Typhimurium
OLFM4
NOTCH
filamentous Salmonella Typhimurium
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2023.2186109

Internet

https://www.tandfonline.com/doi/10.1080/19490976.2023.2186109

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