Increased peptidylarginine deiminases expression during the macrophage differentiation and participated inflammatory responses

Increased peptidylarginine deiminases expression during the macrophage differentiation and participated inflammatory responses

Abstract Objective To investigate the expression of peptidylarginine deiminases (PADIs) during macrophage differentiation and its role in inflammatory responses. Methods The protein expression of PADI2, PADI4, and citrullinated histone 3 in U937 cells, differentiated macrophages, and macrophages sti...

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Bibliographic Details
Main Authors: Ning-Sheng Lai, Hui-Chun Yu, Chien-Hsueh Tung, Kuang-Yung Huang, Hsien-Bin Huang, Ming-Chi Lu
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Arthritis Research & Therapy
Subjects:
Citrullination
Macrophages
PAI-2
PADI2
PADI4
PSMB1
Online Access:http://link.springer.com/article/10.1186/s13075-019-1896-9

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http://link.springer.com/article/10.1186/s13075-019-1896-9

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