Transcriptional and epigenetic regulation of follicular T-helper cells and their role in autoimmunity
T-follicular helper (Tfh) cells are a specialized subset of T cells that provide help to B cells and promote the formation of germinal centers (GCs). Tfh cells transmit important signals to B cells that drive class switch recombination, somatic hyper-mutation, the generation of high-affinity antibod...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2017-02-01
|
Series: | Autoimmunity |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/08916934.2017.1284821 |