Transcriptional and epigenetic regulation of follicular T-helper cells and their role in autoimmunity

T-follicular helper (Tfh) cells are a specialized subset of T cells that provide help to B cells and promote the formation of germinal centers (GCs). Tfh cells transmit important signals to B cells that drive class switch recombination, somatic hyper-mutation, the generation of high-affinity antibod...

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Bibliographic Details
Main Authors: Hong Qiu, Haijing Wu, Vera Chan, Chak-Sing Lau, Qianjin Lu
Format: Article
Language:English
Published: Taylor & Francis Group 2017-02-01
Series:Autoimmunity
Subjects:
Online Access:http://dx.doi.org/10.1080/08916934.2017.1284821