A Leishmania murine model to evaluate the immunomodulatory properties of Pythium insidiosum proteins

Pythium insidiosum immunomodulatory vaccine (PiV) has been tested in clinical and experimental pythiosis. Previous data showed that P. insidiosum immunogens have the ability to switch the Th2 immune response, normally in place during pythiosis, to a curative Th1 response. Pythiosis cannot be reprodu...

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Main Authors: Tatiana Maria Inêz-Ferreira, Leonel Mendoza, Raquel Vilela, Hélida Monteiro de Andrade, João Paulo Haddad, Fernanda Freire Campos Nunes, Isabela Moreira Gondim, Tânia Mara Pinto Dabés Guimarães, Vicente de Paulo Coelho Peixoto de Toledo
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S240584401632357X