Genotoxicity and 28-day repeated dose oral toxicity study of ovatodiolide in rats

Ovatodiolide is a bioactive cembrane-type diterpenoid isolated from Anisomeles indica (L.) Kuntze. It has been proven that ovatodiolide is anti-inflammatory, anti-tumorigenic, anti-melanogenic and attenuates asthma by regulating signaling pathways. The aim of this study was to evaluate the safety of...

Full description

Bibliographic Details
Main Authors: Jing-Chun Chen, Yan-Zhen Dai, Yew-Min Tzeng, Jiunn-Wang Liao
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Toxicology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750021001827